This comprehensive guidebook empowers student leaders to launch and grow American Cancer Society chapters on high school and college campuses. It outlines the mission and impact of ACS student programs, provides step-by-step instructions for starting a chapter, and offers guidance on organizing leadership teams, fundraising, advocacy, patient support, and research initiatives. With practical tools, onboarding support, and access to a national network, the guidebook equips students to make a meaningful difference in the fight against cancer.